Skip to main content



Page 1 of 3

  1. Content type: Research

    Short tandem repeat (STR) analysis of casework samples with low DNA content include those resulting from the transfer of epithelial cells from the skin to an object (e.g., cells on a water bottle, or brim of a...

    Authors: Rosemary S. Turingan, Sameer Vasantgadkar, Luke Palombo, Catherine Hogan, Hua Jiang, Eugene Tan and Richard F. Selden

    Citation: Investigative Genetics 2016 7:2

    Published on:

  2. Content type: Research

    The archeological record indicates that the permanent settlement of Cyprus began with pioneering agriculturalists circa 11,000 years before present, (ca. 11,000 y BP). Subsequent colonization events followed, som...

    Authors: Konstantinos Voskarides, Stéphane Mazières, Despina Hadjipanagi, Julie Di Cristofaro, Anastasia Ignatiou, Charalambos Stefanou, Roy J. King, Peter A. Underhill, Jacques Chiaroni and Constantinos Deltas

    Citation: Investigative Genetics 2016 7:1

    Published on:

  3. Content type: Short report

    According to the dual structure model, the modern Japanese ethnic population consists of a mixture of the Jomon people, who have existed in Japan since at least the New Stone Age, and the Yayoi people, who migrat...

    Authors: Daisuke Miyamori, Noboru Ishikawa, Nozomi Idota, Yasuhiro Kakiuchi, Stuart McLean, Tadaichi Kitamura and Hiroshi Ikegaya

    Citation: Investigative Genetics 2015 6:14

    Published on:

  4. Content type: Research

    Anthropological and genetic data agree in indicating the African continent as the main place of origin for anatomically modern humans. However, it is unclear whether early modern humans left Africa through a s...

    Authors: Francesca Tassi, Silvia Ghirotto, Massimo Mezzavilla, Sibelle Torres Vilaça, Lisa De Santi and Guido Barbujani

    Citation: Investigative Genetics 2015 6:13

    Published on:

  5. Content type: Short report

    The Pacific Oceania region was one of the last regions of the world to be settled via human migration. Here we outline a settlement of this region that has given rise to a uniquely admixed population. The curr...

    Authors: Miles C. Benton, Shani Stuart, Claire Bellis, Donia Macartney-Coxson, David Eccles, Joanne E. Curran, Geoff Chambers, John Blangero, Rod A. Lea and Lyn R. Griffiths

    Citation: Investigative Genetics 2015 6:11

    Published on:

    The Erratum to this article has been published in Investigative Genetics 2015 6:12

  6. Content type: Methodology

    Whole-genome sequencing is performed routinely as a means to identify polymorphic genetic loci such as short tandem repeat loci. We have developed a simple tool, called pSTR Finder, which is freely available a...

    Authors: James Chun-I Lee, Bill Tseng, Bing-Ching Ho and Adrian Linacre

    Citation: Investigative Genetics 2015 6:10

    Published on:

  7. Content type: Short report

    For solving a maternity case, 19 autosomal short tandem repeats (STRs) were amplified using the AmpFℓSTR® SinofilerTM kit and PowerPlex® 16 System. Additional 27 autosomal STR loci were analyzed using two domesti...

    Authors: Li Li, Yuan Lin, Yan Liu, Ruxin Zhu, Zhenmin Zhao and Tingzhi Que

    Citation: Investigative Genetics 2015 6:9

    Published on:

  8. Content type: Review

    Detecting and quantifying the population substructure present in a sample of individuals are of main interest in the fields of genetic epidemiology, population genetics, and forensics among others. To date, se...

    Authors: Andreas Wollstein and Oscar Lao

    Citation: Investigative Genetics 2015 6:7

    Published on:

  9. Content type: Review

    Adaptation can be described as an evolutionary process that leads to an adjustment of the phenotypes of a population to their environment. In the classical view, new mutations can introduce novel phenotypic fe...

    Authors: Andreas Wollstein and Wolfgang Stephan

    Citation: Investigative Genetics 2015 6:5

    Published on:

  10. Content type: Review

    For a long time, the analysis of ancient human DNA represented one of the most controversial disciplines in an already controversial field of research. Scepticism in this field was only matched by the long-las...

    Authors: Michael Knapp, Carles Lalueza-Fox and Michael Hofreiter

    Citation: Investigative Genetics 2015 6:4

    Published on:

  11. Content type: Research

    Mammalian hairs are one of the most ubiquitous types of trace evidence collected in the course of forensic investigations. However, hairs that are naturally shed or that lack roots are problematic substrates f...

    Authors: Silvana R Tridico, Dáithí C Murray, Jayne Addison, Kenneth P Kirkbride and Michael Bunce

    Citation: Investigative Genetics 2014 5:16

    Published on:

  12. Content type: Research

    The peopling of Europe and the nature of the Neolithic agricultural migration as a primary issue in the modern human colonization of the globe is still widely debated. At present, much uncertainty is associate...

    Authors: Anahit Hovhannisyan, Zaruhi Khachatryan, Marc Haber, Peter Hrechdakian, Tatiana Karafet, Pierre Zalloua and Levon Yepiskoposyan

    Citation: Investigative Genetics 2014 5:15

    Published on:

  13. Content type: Research

    Comparisons of maternally-inherited mitochondrial DNA (mtDNA) and paternally-inherited non-recombining Y chromosome (NRY) variation have provided important insights into the impact of sex-biased processes (suc...

    Authors: Sebastian Lippold, Hongyang Xu, Albert Ko, Mingkun Li, Gabriel Renaud, Anne Butthof, Roland Schröder and Mark Stoneking

    Citation: Investigative Genetics 2014 5:13

    Published on:

  14. Content type: Research

    Crops in the USA are vulnerable to natural and criminal threats because of their widespread cultivation and lack of surveillance, and because of implementation of growing practices such as monoculture. To prep...

    Authors: Mindy James, Ulrich Melcher and Jacqueline Fletcher

    Citation: Investigative Genetics 2014 5:10

    Published on:

  15. Content type: Review

    High throughput sequencing (HTS) generates large amounts of high quality sequence data for microbial genomics. The value of HTS for microbial forensics is the speed at which evidence can be collected and the p...

    Authors: Bruce Budowle, Nancy D Connell, Anna Bielecka-Oder, Rita R Colwell, Cindi R Corbett, Jacqueline Fletcher, Mats Forsman, Dana R Kadavy, Alemka Markotic, Stephen A Morse, Randall S Murch, Antti Sajantila, Sarah E Schmedes, Krista L Ternus, Stephen D Turner and Samuel Minot

    Citation: Investigative Genetics 2014 5:9

    Published on:

  16. Content type: Research

    In forensic science there are many types of crime that involve animals. Therefore, the identification of the species has become an essential investigative tool. The exhibits obtained from such offences are ver...

    Authors: Elena Pilli, Rosario Casamassima, Stefania Vai, Antonino Virgili, Filippo Barni, Giancarlo D’Errico, Andrea Berti, Giampietro Lago and David Caramelli

    Citation: Investigative Genetics 2014 5:7

    Published on:

  17. Content type: Review

    In 1962, Thomas Kuhn famously argued that the progress of scientific knowledge results from periodic ‘paradigm shifts’ during a period of crisis in which new ideas dramatically change the status quo. Although thi...

    Authors: Geoffrey K Chambers, Caitlin Curtis, Craig D Millar, Leon Huynen and David M Lambert

    Citation: Investigative Genetics 2014 5:3

    Published on:

  18. Content type: Review

    Almost three decades ago Alec Jeffreys published his seminal Nature papers on the use of minisatellite probes for DNA fingerprinting of humans (Jeffreys and colleagues Nature 1985, 314:67–73 and Nature 1985, 316:...

    Authors: Hilde Nybom, Kurt Weising and Björn Rotter

    Citation: Investigative Genetics 2014 5:1

    Published on:

  19. Content type: Research

    Wildlife collisions with aircraft cost the airline industry billions of dollars per annum and represent a public safety risk. Clearly, adapting aerodrome habitats to become less attractive to hazardous wildlif...

    Authors: Megan L Coghlan, Nicole E White, Dáithí C Murray, Jayne Houston, William Rutherford, Matthew I Bellgard, James Haile and Michael Bunce

    Citation: Investigative Genetics 2013 4:27

    Published on:

  20. Content type: Methodology

    Mitochondrial DNA (mtDNA) typing can be a useful aid for identifying people from compromised samples when nuclear DNA is too damaged, degraded or below detection thresholds for routine short tandem repeat (STR...

    Authors: Jennifer E L Templeton, Paul M Brotherton, Bastien Llamas, Julien Soubrier, Wolfgang Haak, Alan Cooper and Jeremy J Austin

    Citation: Investigative Genetics 2013 4:26

    Published on:

  21. Content type: Review

    DNA fingerprinting, one of the great discoveries of the late 20th century, has revolutionized forensic investigations. This review briefly recapitulates 30 years of progress in forensic DNA analysis which help...

    Authors: Lutz Roewer

    Citation: Investigative Genetics 2013 4:22

    Published on:

  22. Content type: Research

    Teeth are a valuable source of DNA for identification of fragmented and degraded human remains. While the value of dental pulp as a source of DNA is well established, the quantity and presentation of DNA in th...

    Authors: Denice Higgins, John Kaidonis, Grant Townsend, Toby Hughes and Jeremy J Austin

    Citation: Investigative Genetics 2013 4:18

    Published on:

  23. Content type: Research

    The generation of short tandem repeat profiles, also referred to as ‘DNA typing,’ is not currently performed outside the laboratory because the process requires highly skilled technical operators and a control...

    Authors: Eugene Tan, Rosemary S Turingan, Catherine Hogan, Sameer Vasantgadkar, Luke Palombo, James W Schumm and Richard F Selden

    Citation: Investigative Genetics 2013 4:16

    Published on:

  24. Content type: Research

    Accurate determination of genetic ancestry is of high interest for many areas such as biomedical research, personal genomics and forensics. It remains an important topic in genetic association studies, as it h...

    Authors: Caroline M Nievergelt, Adam X Maihofer, Tatyana Shekhtman, Ondrej Libiger, Xudong Wang, Kenneth K Kidd and Judith R Kidd

    Citation: Investigative Genetics 2013 4:13

    Published on: