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Table 4 Gaps in our knowledge related to surrogate selection and model parameters.

From: Identifying experimental surrogates for Bacillus anthracis spores: a review

Gaps

Recommended action

No quantitative comparisons of spore survival on fomites

Conduct experiments using steel, laminar, plastic and other surfaces

No quantitative comparisons of spore survival in soil

Conduct experiments across soil types

No quantitative comparisons of spore survival in buffer/water

Conduct survival experiments in water or buffer

No long-term studies

Perform spore survival studies that are over a year long

Only one comparative study examining the effect of heat in various buffers

Reconfirm results

Only one comparative study with UV

Reconfirm results

Only a few studies with virulent Bacillus anthracis

Use virulent B. anthracis and compare directly to potential surrogates