Table 2 Practical attributes in surrogate selection
From: Identifying experimental surrogates for Bacillus anthracis spores: a review
Attribute | Remarks |
|---|---|
Safety | Should not cause illness or infection in animals or plants |
Ease of culture | Able to produce with standard microbiological methods in a reasonable timeframe and have reproducibility |
History of use | Possibility of attaining comparative information from the literature and judging surrogate behaviour |
Ease and speed of detection | Allows large numbers of samples to be processed for rapid feedback of results |
Cost | Surrogate production and detection should not be excessive |
Stability or persistence | No long-term persistence, or easily decontaminated |
Practical for industrial testing | Should not damage equipment or processes |