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Figure 1 | Investigative Genetics

Figure 1

From: Long-term RNA persistence in postmortem contexts

Figure 1

Structure of RNA and process of hydrolysis. (A) Chemical structure of RNA. The ribose, bases and phosphate group are labeled. The 2′-hydroxyl group (labeled) allows the RNA molecule to be more easily degraded via hydrolysis than DNA. Similarly, the phosphodiester bond (also labeled) in RNA can be broken during hydrolysis. The N-glycosidic bond (labeled) is stronger in RNA than DNA. (B) The chemical process of hydrolysis, where the 2′-hydroxyl group has attacked the adjacent phosphodiester bond, cleaving the backbone of the RNA.

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