BioChipSet cassette. (A) Top view schematic showing the location of the smart cartridge, gel smart cartridge, and integrated biochip. (B) Bottom view schematic showing the S&D biochip. (C) Photograph. Primary interfaces with the instrument are via the pneumatic manifold, PCR chambers, cathode and anode (not shown, adjacent to the gel smart cartridge), and S&D window. S&D, separation and detection; SC, smart cartridge.