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Figure 3 | Investigative Genetics

Figure 3

From: High diversity and no significant selection signal of human ADH1B gene in Tibet

Figure 3

Long-range haplotype networks of ADH1B. We examined 23 SNPs covering 173.5 kb of the ADH region, extending from rs1154473 upstream (telomeric) of ADH7 through ADH1C, ADH1B (including ADH1B*48His), and ADH1A to rs1230025 downstream (centromeric) of the ADH1 cluster. For haplogroups H5, H6, and H7 the relationships among the haplotypes of 23 SNPs were displayed by networks using Network 4.5.1.6. The ‘Tibetan larger’ included 909 individuals from central Tibet (Qamdo 157, Lhasa 334, Nagqu 24, Nyingchi 55, Shannan 147, Shigatse 192), while the ‘Tibetan smaller’ included 216 individuals distributed in other parts of Tibet (Gongbo 50, Tingri 50, Lhoba 50, Monba 16, Deng 50, and Sherpa 50). The reference samples are all the population data from reference [12].

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