Table 1 Heritability estimates of various complex diseases and traits
From: An epidemiological perspective on the future of direct-to-consumer personal genome testing
Disease or trait | Heritability | Reference |
|---|---|---|
Eye color | > 99% | [18] |
Type 1 diabetes | 88% | [19] |
Schizophrenia | 81% | [20] |
Alzheimer's disease | 79% | [21] |
Height | 70-87% (m), 68-85% (v) | [22] |
Obesity | 65-84% (m), 64-79% (w) | [23] |
Smoking persistence | 59% (m), 46% (w) | [24] |
Anorexia nervosa | 56% | [25] |
Rheumatoid arthritis | 53-65% | [26] |
Panic disorder | 43% | [27] |
Prostate cancer | 42% | [28] |
Migraine | 40-50% | [29] |
Heart attack | 38% (m), 57% (w) | [30] |
Smoking initiation | 37% (m), 55% (w) | [24] |
Depression | 37% | [31] |
Colorectal cancer | 35% | [28] |
Anxiety disorder | 32% | [27] |
Homosexuality | 30% (m), 50-60% (w) | [32] |
Breast cancer | 27% | [28] |
Type 2 diabetes | 26% | [33] |
Lung cancer | 26% | [28] |
Happiness | 22% (m), 41% (w) | [34] |