Criteria for selecting microhaplotypes: mixture detection and deconvolution

Investigative Genetics

Table 1 Maximum probabilities of detecting a mixture of two random unrelated individuals for an N-allele microhap

Number of equally frequent alleles	Probability of three alleles being present	Probability of four alleles being present	Total probability of detecting more than two alleles in a mixture
Three	0.4444	-	0.4444
Four	0.5625	0.09375	0.65625
Five	0.5760	0.1920	0.7680

Maximum probabilities of detecting a mixture of two random unrelated individuals for three-, four-, and five-allele microhaps. These are the values when all alleles are equally frequent. As shown in Figure 1, the values are lower when the frequencies are not equal.

ISSN: 2041-2223