Parameter

Prior

Median

95% CI


Ne_{YRI}

U_{(500,10000)}

5070

(2400  8930)

Ne_{CEU}

U_{(500,5000)}

1630

(130  6900)

Ne_{CHB}

U_{(500,5000)}

4720

(1920  7650)

Ne_{CEU_CHB}

U_{(500,5000)}

4390

(1420  8890)

Ne_{A}

U_{(500,5000)}

4800

(2160  8900)

t_{SplitCEU_CHB}

U_{(0.17, 0.83)}^{b}

45,250

(11,500  63,250)

t_{SplitOAA}

U_{(100,000, 325,000)}

52,250

(50,250  76,000)

 CI, confidence interval.
 ^{a}Estimated by approximate bayesian computation/Markov chain Monte Carlo (ABCMCMC) from regions of 10 kb each from 50 genes from the Environmental Genome Project database with a burnin of 1,000 simulations, 9,000 retained simulations and a thinning of 9. The total number of iterations retained for estimating the posterior distributions was 1,000. Times are computed in years as the number of generations multiplied by an estimated generation time of 25 years, and a scaling factor of 10 that was used (μ was set constant to 2.35 × 10^{7} after scaling by 10). Effective population sizes are in number of diploid individuals after correcting by the scaling factor of 10.
 ^{b}Time of split of CEU and CHB as a function of the remaining time after the outofAfrica split. A value of 1 would indicate that CEU and CHB split just after the outofAfrica split.