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Table 3 SNP detection performance in B. anthracis A2012 versus Sterne

From: Accurate, rapid and high-throughput detection of strain-specific polymorphisms in Bacillus anthracis and Yersinia pestis by next-generation sequencing

 

FNb, n

FPc, n

Sensitivity, %

Specificity, %

Total

20

8

86.67

99.99985

Excluding SNP clustersa

3

8

97.74

99.99985

  1. a17 SNPs in two clusters: 13/40 bp (GBAA_2450) and 4/10 bp (PBP).
  2. bFalse negative.
  3. cFalse positive.
  4. SNP, single-nucleotide polymorphism.
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Investigative Genetics

ISSN: 2041-2223

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